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What do we know so far about COVID-19 losing its potency?

What do we know so far about COVID-19 losing its potency?

This article was published on
June 1, 2020

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There is no evidence to support the idea that the virus has lost its potency. This question likely stems from comments made by an Italian doctor claiming that COVID-19 is losing its potency by mutating into a less harmful version of itself. However, this has been refuted by the World Health Organization and other respected health and medical bodies. Viral mutations are a common aspect of a virus' lifespan and do not necessarily mean that they will become more deadly, contagious, or inherently different. Mutations that might change how the virus is transmitted, or how it infects people, does not mean that the mutated virus will spread more or be more harmful. Nor does it mean it will spread less or be less harmful. So far, researchers have stated that while the virus is mutating (like all viruses do) these changes do not translate to significant adjustments in transmission or harm to patients.

There is no evidence to support the idea that the virus has lost its potency. This question likely stems from comments made by an Italian doctor claiming that COVID-19 is losing its potency by mutating into a less harmful version of itself. However, this has been refuted by the World Health Organization and other respected health and medical bodies. Viral mutations are a common aspect of a virus' lifespan and do not necessarily mean that they will become more deadly, contagious, or inherently different. Mutations that might change how the virus is transmitted, or how it infects people, does not mean that the mutated virus will spread more or be more harmful. Nor does it mean it will spread less or be less harmful. So far, researchers have stated that while the virus is mutating (like all viruses do) these changes do not translate to significant adjustments in transmission or harm to patients.

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What our experts say

There is no evidence to support the idea that the virus has lost its potency. This question likely stems from comments made by an Italian doctor claiming that COVID-19 is losing its potency by mutating into a less harmful version of itself. However, this has been refuted by the World Health Organization and other respected health and medical bodies.

Viral mutations are a common aspect of a virus' lifespan and do not necessarily mean that they will become more deadly, contagious, or inherently different. Mutations that might change how the virus is transmitted, or how it infects people, does not mean that the mutated virus will spread more or be more harmful. Nor does it mean it will spread less or be less harmful. So far, researchers have stated that while the virus is mutating (like all viruses do) these changes do not translate to significant adjustments in transmission or harm to patients.

There is no evidence to support the idea that the virus has lost its potency. This question likely stems from comments made by an Italian doctor claiming that COVID-19 is losing its potency by mutating into a less harmful version of itself. However, this has been refuted by the World Health Organization and other respected health and medical bodies.

Viral mutations are a common aspect of a virus' lifespan and do not necessarily mean that they will become more deadly, contagious, or inherently different. Mutations that might change how the virus is transmitted, or how it infects people, does not mean that the mutated virus will spread more or be more harmful. Nor does it mean it will spread less or be less harmful. So far, researchers have stated that while the virus is mutating (like all viruses do) these changes do not translate to significant adjustments in transmission or harm to patients.

Context and background

Viruses reproduce themselves in bodies by injecting their DNA or RNA into cells in the body. The genetic material from that injection becomes a blueprint for how to make more and more of the virus. Eventually the cells in our bodies recognize the virus, and develop new ways to prevent it from duplicating. So viruses adapt by mutating, which disguises them once again from our immune systems so they can continue to duplicate. Mutation for viruses simply means a change or transformation. RNA viruses, like SARS-CoV-2 which causes COVID-19, mutate a lot. It is important to track these mutations to understand the various identities of the virus and map its trends across the world. However, as these changes happen, it's also important to understand what adaptation the virus is taking and what are their consequences on human health. It's important to keep in mind that mutations might not translate to drastic changes in severity of the illness or increase its mortality. Mutations are a natural process for RNA viruses and should not be seen as an indicator for suddenly a newer, deadlier virus. Understanding these viral changes and genomic epidemiology can help us understand outbreaks better.

Viruses reproduce themselves in bodies by injecting their DNA or RNA into cells in the body. The genetic material from that injection becomes a blueprint for how to make more and more of the virus. Eventually the cells in our bodies recognize the virus, and develop new ways to prevent it from duplicating. So viruses adapt by mutating, which disguises them once again from our immune systems so they can continue to duplicate. Mutation for viruses simply means a change or transformation. RNA viruses, like SARS-CoV-2 which causes COVID-19, mutate a lot. It is important to track these mutations to understand the various identities of the virus and map its trends across the world. However, as these changes happen, it's also important to understand what adaptation the virus is taking and what are their consequences on human health. It's important to keep in mind that mutations might not translate to drastic changes in severity of the illness or increase its mortality. Mutations are a natural process for RNA viruses and should not be seen as an indicator for suddenly a newer, deadlier virus. Understanding these viral changes and genomic epidemiology can help us understand outbreaks better.

Resources

  1. We shouldn’t worry when a virus mutates during disease outbreaks (Nature)
  1. We shouldn’t worry when a virus mutates during disease outbreaks (Nature)

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