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Can cannabis prevent, treat or cure COVID-19?

Can cannabis prevent, treat or cure COVID-19?

This article was published on
June 1, 2020

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There is no reliable evidence so far to suggest that cannabis can prevent, treat or cure COVID-19. One pre-print (a type of study that is yet to be peer-reviewed) from Canada suggests possible anti-inflammatory properties in cannabis may be effective in future treatments of the disease. The study also suggests that cannabis could be used to prevent infection from the SARS-CoV-2 virus that causes COVID-19. SARS-CoV-2 gains entry into cells in the human body by interacting with the ACE2 receptor protein, which is found on the surface of many cells. This study suggests that cannabidiol (CBD), one of the active ingredients in cannabis, may affect the virus' ability to bind to the ACE2 receptor protein and enter cells. However, none of the claims in the pre-print study have been validated in large-scale studies, and pre-print data should always be treated with caution. Another lab, in Israel, is studying the effects of cannabis on the immune system's response to COVID-19 and analyzing the potential for molecules in cannabis to prevent the virus from entering cells and spreading. This research, however, has been undertaken by a cannabis research and development company based in Israel, and not independently verified by other scientific studies that are not linked to the cannabis industry. At this point, there is insufficient independent research to make any claims about the use of cannabis in preventing, treating, or curing COVID-19.

There is no reliable evidence so far to suggest that cannabis can prevent, treat or cure COVID-19. One pre-print (a type of study that is yet to be peer-reviewed) from Canada suggests possible anti-inflammatory properties in cannabis may be effective in future treatments of the disease. The study also suggests that cannabis could be used to prevent infection from the SARS-CoV-2 virus that causes COVID-19. SARS-CoV-2 gains entry into cells in the human body by interacting with the ACE2 receptor protein, which is found on the surface of many cells. This study suggests that cannabidiol (CBD), one of the active ingredients in cannabis, may affect the virus' ability to bind to the ACE2 receptor protein and enter cells. However, none of the claims in the pre-print study have been validated in large-scale studies, and pre-print data should always be treated with caution. Another lab, in Israel, is studying the effects of cannabis on the immune system's response to COVID-19 and analyzing the potential for molecules in cannabis to prevent the virus from entering cells and spreading. This research, however, has been undertaken by a cannabis research and development company based in Israel, and not independently verified by other scientific studies that are not linked to the cannabis industry. At this point, there is insufficient independent research to make any claims about the use of cannabis in preventing, treating, or curing COVID-19.

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What our experts say

There is no reliable evidence so far to suggest that cannabis can prevent, treat or cure COVID-19. One pre-print (a type of study that is yet to be peer-reviewed) from Canada suggests possible anti-inflammatory properties in cannabis may be effective in future treatments of the disease. The study also suggests that cannabis could be used to prevent infection from the SARS-CoV-2 virus that causes COVID-19. SARS-CoV-2 gains entry into cells in the human body by interacting with the ACE2 receptor protein, which is found on the surface of many cells. This study suggests that cannabidiol (CBD), one of the active ingredients in cannabis, may affect the virus' ability to bind to the ACE2 receptor protein and enter cells. However, none of the claims in the pre-print study have been validated in large-scale studies, and pre-print data should always be treated with caution.

Another lab, in Israel, is studying the effects of cannabis on the immune system's response to COVID-19 and analyzing the potential for molecules in cannabis to prevent the virus from entering cells and spreading. This research, however, has been undertaken by a cannabis research and development company based in Israel, and not independently verified by other scientific studies that are not linked to the cannabis industry. At this point, there is insufficient independent research to make any claims about the use of cannabis in preventing, treating, or curing COVID-19.

There is no reliable evidence so far to suggest that cannabis can prevent, treat or cure COVID-19. One pre-print (a type of study that is yet to be peer-reviewed) from Canada suggests possible anti-inflammatory properties in cannabis may be effective in future treatments of the disease. The study also suggests that cannabis could be used to prevent infection from the SARS-CoV-2 virus that causes COVID-19. SARS-CoV-2 gains entry into cells in the human body by interacting with the ACE2 receptor protein, which is found on the surface of many cells. This study suggests that cannabidiol (CBD), one of the active ingredients in cannabis, may affect the virus' ability to bind to the ACE2 receptor protein and enter cells. However, none of the claims in the pre-print study have been validated in large-scale studies, and pre-print data should always be treated with caution.

Another lab, in Israel, is studying the effects of cannabis on the immune system's response to COVID-19 and analyzing the potential for molecules in cannabis to prevent the virus from entering cells and spreading. This research, however, has been undertaken by a cannabis research and development company based in Israel, and not independently verified by other scientific studies that are not linked to the cannabis industry. At this point, there is insufficient independent research to make any claims about the use of cannabis in preventing, treating, or curing COVID-19.

Context and background

In recent years, there has been a significant interest in the development of therapies and other consumer products derived from cannabis and its components, including cannabidiol (CBD). The U.S. FDA has approved only one CBD product, a prescription drug product to treat two rare, severe forms of epilepsy. In the context of COVID-19, media reported the results of a preprint study indicating the possibility that cannabis could prevent COVID-19 by blocking the virus' entry into the lungs. This study has not gone through the peer review process, has not been assessed by peers, and has not published in any scientific journal.

In recent years, there has been a significant interest in the development of therapies and other consumer products derived from cannabis and its components, including cannabidiol (CBD). The U.S. FDA has approved only one CBD product, a prescription drug product to treat two rare, severe forms of epilepsy. In the context of COVID-19, media reported the results of a preprint study indicating the possibility that cannabis could prevent COVID-19 by blocking the virus' entry into the lungs. This study has not gone through the peer review process, has not been assessed by peers, and has not published in any scientific journal.

Resources

  1. Could cannabis terpene formulation treat COVID-19? (Health Europa)
  2. Cannabidiol (CBD): what we know and what we don't (Harvard)
  3. NIH Research on Marijuana and Cannabinoids (National Institute on Drug Abuse)
  4. In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues (Preprints)
  1. Could cannabis terpene formulation treat COVID-19? (Health Europa)
  2. Cannabidiol (CBD): what we know and what we don't (Harvard)
  3. NIH Research on Marijuana and Cannabinoids (National Institute on Drug Abuse)
  4. In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues (Preprints)

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